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5T4-directed γδ T cell engagement in solid tumors

Publication

This publication describes a 5T4-directed Vδ2 bispecific T cell engager designed to recruit Vγ9Vδ2 T cells against solid tumor cells. The work adds to the scientific foundation for using unconventional T cells to support tumor-selective immune responses.

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CD1d-directed single-domain antibodies uniquely activate type 1 NKT-cells

Publication

This foundational study describes a single-domain bispecific antibody approach targeting CD1d and the type 1 NKT T cell receptor. The work adds to the scientific basis for exploring unconventional T cell:cell biology in cancer immunotherapy.

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