Pipeline

Pipeline

Building a pipeline of unconventional T cell engagers

Engager BIO is advancing a focused pipeline with a clinical stage first generation γδ T cell engager to be tested in a rational combination therapy approach, and multiple next-generation programs designed to address unmet medical needs across patients with solid tumors and hematologic malignancies.

Candidate
Target
Indication(s)
Development stage
Discovery Preclinical Phase 1 Phase 2
Remarks
ENG-1001*
CD123
AML MDS
1st line; combination Tx 1st line; combination Tx
ENG-2001
ND
Solid tumor
Next-generation; CLD ready
ENG-2002
ND
Solid tumor
Next-generation; CLD ready
ENG-2xxx
ND
Solid/heme
Next-generation